Affiliation between anti-ADAMTS13 antibody and the pathophysiology of antiphospholipid syndrome, which needs to be additional evaluated
Though a number of antiphospholipid syndrome (APS) happens with acquired thrombotic thrombocytopenic purpura (TTP), the connection between antiphospholipid antibodies (aPL) and anti-ADAMTS13 (anti-a disintegrin and metalloprotease with thrombospondin kind 1 motif, member 13) antibody stays unsure.
We investigated the connection between high-risk thrombotic aPL and anti-ADAMTS13 antibody. 2 hundred and thirty-seven sufferers with constructive lupus anticoagulant and/or anticardiolipin antibody have been included. Anti-β2GPI (anti-β2-glycoprotein I), anti-β2GPIdI (anti-β2-glycoprotein I area I), anti-PS/PT (anti-phosphatidylserine and prothrombin), ADAMTS13 exercise, and anti-ADAMTS13 antibody have been measured.
Double positivity of anti-β2GPI and anti-PS/PT elevated thrombotic danger greater than three-fold and confirmed elevated positivity of anti-ADAMTS13 antibody compared with the double destructive group.
Double positivity of anti-β2GPIdI and anti-PS/PT introduced each results much more. Within the linear regression evaluation, double positivity of anti-β2GPI and anti-PS/PT independently affected the anti-ADAMTS13 antibody stage (β = 1.982, P = 0.042).
Our outcomes revealed that double positivity of anti-β2GPI or anti-β2GPIdI and anti-PS/PT elevated not solely thrombotic danger but additionally the positivity of anti-ADAMTS13 antibody, particularly indicating anti-β2GPIdI confirmed the next synergistic impact with anti-PS/PT. We propose a attainable affiliation of anti-ADAMTS13 antibody with a excessive thrombotic danger of APS.
Double positivity of anti-β2GPI (anti-β2-glycoprotein I) and anti-PS/PT (anti-phosphatidylserine and prothrombin) antibodies enhanced not solely thrombotic danger but additionally positivity of anti-ADAMTS13 (anti-a disintegrin and metalloprotease with thrombospondin kind 1 motif, member 13) antibody.
Moreover, double positivity of anti-β2GPIdI (anti-β2-glycoprotein I area I) mixed with anti-PS/PT much more elevated each thrombosis and positivity of anti-ADAMTS13 antibody. Double positivity of β2GPI and anti-PS/PT was discovered as an independently important contributing issue to anti-ADAMTS13 antibody stage. We propose the affiliation between anti-ADAMTS13 antibody and the pathophysiology of antiphospholipid syndrome, which needs to be additional evaluated.
Demographic knowledge, neurological signs, comorbidity with diabetes mellitus (DM) or with one other autoimmune illness, and GAD-Abs titers have been studied
Targets: To discover totally different neurological manifestations with suspicion of being related to serum glutamate decarboxylase antibodies (GAD-Abs) in order to raised characterize anti-GAD neurological syndromes.
Strategies: Observational retrospective research together with all sufferers for whom GAD65-Abs titers in serum have been requested by the Neurology Division at La Paz College Hospital between 2015 and 2019. GAD-Abs have been measured by ELISA. Demographic knowledge, neurological signs, comorbidity with diabetes mellitus (DM) or with one other autoimmune illness, and GAD-Abs titers have been studied. Stiff-person syndrome, ataxia, encephalitis, and epilepsy have been thought-about typical anti-GAD neurological syndromes and have been in comparison with different atypical manifestations.
Outcomes: A complete of 173 sufferers (51.7% males, imply age 51.62) have been included. A progressive enhance in requests of serum GAD-Abs has occurred during the last 5 years, particularly in sufferers with atypical neurological manifestations. GAD-Abs have been discovered within the serum of 22 sufferers (12.7%); of these, 15 (68.18%) suffered a typical anti-GAD syndrome.
Presence of DM or one other organ-specific autoimmune illness was predictive of GAD-AB seropositivity (p < 0.001). 6.6% of requested sufferers with an atypical syndrome had GAD-Abs, however serum ranges have been considerably decrease than these present in sufferers with a typical syndrome (706.67 vs 1430.23 UI/mL; Mann-Whitney U, p = 0.034), and have been lastly identified with one other neurological illness.
Conclusion: Serum GAD-Abs have been occasionally present in sufferers with medical phenotypes aside from these classically described as anti-GAD problems, and with very low titers. In typical anti-GAD syndromes, there’s a excessive comorbidity with DM and with different autoimmune illnesses, and excessive serum GAD-Abs ranges are often current.
Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
Description: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.
Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.
Description: This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 7A in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse Semaphorin 3
in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 4D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Semaphorin 6D in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse semaphorin 3G in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170
Description: A polyclonal antibody for detection of Rab 6A from Human, Mouse, Rat. This Rab 6A antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Rab 6A at AA range: 90-170
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the antibodies and the focused cell, which often leads to the simultaneous immune-mediated mobile destruction
The recruitment of endogenous antibodies in opposition to most cancers cells has develop into a dependable antitumoral immunotherapeutic various during the last decade. The covalent attachment of antibody and tumor binding modules (ABM and TBM) inside a single, well-defined artificial molecule was certainly demonstrated to advertise the formation of an interacting ternary complicated between each the antibodies and the focused cell, which often leads to the simultaneous immune-mediated mobile destruction. In a preliminary research, we’ve got described the first Antibody Recruiting Glycodendrimers (ARGs), combining cRGD as ligands for the αVβ3-expressing melanoma cell line M21 and Rha as ligand for pure IgM, and demonstrated that multivalency is an important requirement to kind this complicated.
Within the current research, we synthesized a brand new sequence of ARGs composed of ABMs, i.e. self-condensed rhamnosylated cyclopeptide and polylysine dendrimer, which have been conjugated to the TBM with or with out spacer. Movement cytometry and confocal microscopy experiments with human serum and totally different cell strains revealed that the ABM geometry considerably influences the ternary complicated formation in M21, whereas no important binding happens in BT 549 having low integrin expression.
As well as, we reveal with a mobile viability assay that ARGs induce excessive stage of cytotoxicity in opposition to M21 which can also be in shut correlation with the ABM construction. Specifically, we’ve got proven that ARG combining cyclopeptide core and branches, with or with out spacer, induce 40-57% of selective cytotoxicity in opposition to M21 cells within the presence of human serum because the distinctive supply of immunity effectors. Lastly, we additionally spotlight that the spacer between ABM and TBM allows a rise of the immune-mediate cytotoxicity even with ABM of decrease valency.
synthesized coating antigen was used to display screen the monoclonal antibody (mAb)
Diazinon (DAZ) is an organophosphorus pesticide (OP), which is often used to stop and management dangerous pests that endanger agricultural merchandise. On this research, we developed a novel heterology coating technique for the immunoassay of DAZ. The DAZ coating hapten could be immediately conjugated to the service protein with out requiring a spacer arm.
This proposed hapten coating technique is time-saving and considerably improves the sensitivity of the immunoassay as a result of lack of a spacer arm. The as-synthesized coating antigen was used to display screen the monoclonal antibody (mAb).
Lastly, the developed oblique aggressive enzyme-linked immunoassay (icELISA) confirmed IC50 and restrict of detection (LOD) values of 0.58 ng mL-1 and eight pg mL-1, respectively. This methodology exhibited negligible cross-reactivity in direction of different analogues, and the recoveries of samples (cucumber, cabbage, and lettuce) ranged from 92.6% to 125.4%, with coefficients of variance (CV) beneath 12%. Good correlation between icELISA and high-performance liquid chromatography mass spectrometry (HPLC-MS/MS) was obtained. The proposed icELISA was a perfect instrument for monitoring DAZ residues in meals samples.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Nitrotyrosine (NT) in samples from serum, plasma, tissue homogenates or other biological fluids.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Nitrotyrosine (NT) in samples from serum, plasma, tissue homogenates or other biological fluids.
Description: NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Neurotensin (NT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Neurotensin (NT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
Description: The plasma concentrations of both the N-terminal fragment of Pro-B-type natriuretic peptide (NT-proBNP) and prohormone of brain natriuretic peptide (proBNP) are significantly increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
Description: The plasma concentrations of both the N-terminal fragment of Pro-B-type natriuretic peptide (NT-proBNP) and prohormone of brain natriuretic peptide (proBNP) are significantly increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human N-Terminal Pro C-Type Natriuretic Peptide (NT-ProCNP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Human N-Terminal Pro C-Type Natriuretic Peptide (NT-ProCNP) ELISA Kit
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human N-Terminal Pro C-Type Natriuretic Peptide (NT-ProCNP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Human N-Terminal Pro C-Type Natriuretic Peptide (NT-ProCNP) ELISA Kit
Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human Neurotrophin-3, NT-3 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Human 3-nitrotyrosine (3-NT) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human 3-nitrotyrosine (3-NT) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Neurotrophin-3 Human Recombinant produced in E.Coli is a non-glycosylated and non-covalently linked homodimer, containing 2x119 amino acid chains, having a total Mw of 27.2 kDa.;The NT-3 is purified by proprietary chromatographic techniques.
Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical.
Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues). Human and Mouse NT-3 sequences are identical.
Description: NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6 kDa polypeptide monomers (240 total amino acid residues).Human and Mouse NT-3 sequences are identical.
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Description: A polyclonal antibody for detection of NT-3 from Human, Mouse, Rat. This NT-3 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NT-3 . This antibody is tested and proven to work in the following applications:
Description: Description of target: Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system. NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis. NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation. NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo.4 NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 2 pg/mL
Description: A sandwich quantitative ELISA assay kit for detection of Mouse N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Rat N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Canine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Canine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Porcine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Porcine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma or other biological fluids.
Porcine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Porcine N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma or other biological fluids.
Rat N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rat N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rabbit N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Rabbit N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit N-Terminal Pro Brain Natriuretic Peptide (NT-ProBNP) in samples from serum, plasma, tissue homogenates or other biological fluids.
Mouse N-Terminal Pro Atrial Natriuretic Peptide (NT-ProANP) ELISA Kit
